PHT533 - Pharmacology and Applied Toxicology

Outline information
Schools offering this subject
Last revision date Feb 3, 2021 11:10:47 AM
Last review date Feb 3, 2021 11:10:47 AM

Subject Title
Pharmacology and Applied Toxicology

Subject Description
This course is designed to introduce students to basic pharmacological and toxicological principles through the selective coverage of various topics in pharmacodynamics, pharmacokinetics, medicinal chemistry, drug design and toxicology. Laboratory experiments will focus on commonly used techniques (solid phase extraction, HPLC, GC, TLC) and biological matrices (blood, urine, and saliva) encountered in a pharmacology or toxicology laboratory setting.

Credit Status
Programs: CLT, CLP
One credit towards CLP program.

Learning Outcomes
Upon successful completion of this subject the student will be able to:

General Lecture Objectives: Upon successful completion of this course, the student will be able to:

  1. Understand the basic principles of pharmacology, pharmacokinetics and pharmacodynamics.
  2. Understand the basic principles of ADME, toxicology and dose response.
  3. Perform basic interpretation of drug pharmacokinetic profiles and pharmacodynamics related to ADME and bioavailability.
  4. Understand general concepts in toxicology and adverse drug reactions.
  5. Understand basic human physiology as it relates to drug therapeutics and drug mechanism.
  6. Understand drug-drug interactions and their therapeutic effects on human body.
  7. Understand the concept of drug design by rationale and identify pharmacologically active structures.
  8. Understand the autonomic and somatic nervous system and neurotransmitter-receptor interaction.
  9. In depth analysis of antimicrobial agents and their chemical structures
  10. Review the current selected topics in modern pharmacology.
Laboratory Experiments: Upon successful completion of this course, the student will be able to:
  1. Perform analysis of drugs in complex matrices using a variety of sample preparation techniques and analytical measurements applicable to a pharmacology and toxicology laboratory setting.
  2. Develop laboratory skills required for future employment.
  3. Use observational and critical thinking skills to make appropriate conclusions pertaining to pharmacological/toxicological sample analysis.

Essential Employability Skills

    •  Communicate clearly, concisely and correctly in the written, spoken and visual form that fulfils the purpose and meets the needs of the audience.

    •  Respond to written, spoken, or visual messages in a manner that ensures effective communication.

    •  Execute mathematical operations accurately.

    •  Apply a systematic approach to solve problems.

    •  Use a variety of thinking skills to anticipate and solve problems.

    •  Locate, select, organize, and document information using appropriate technology and information systems.

    •  Analyze, evaluate, and apply relevant information from a variety of sources.

    •  Show respect for diverse opinions, values, belief systems, and contributions of others.

    •  Interact with others in groups or teams in ways that contribute to effective working relationships and the achievement of goals.

    •  Manage the use of time and other resources to complete projects.

    •  Take responsibility for one's own actions, decisions, and consequences.

Academic Integrity
Seneca upholds a learning community that values academic integrity, honesty, fairness, trust, respect, responsibility and courage. These values enhance Seneca's commitment to deliver high-quality education and teaching excellence, while supporting a positive learning environment. Ensure that you are aware of Seneca's Academic Integrity Policy which can be found at: Review section 2 of the policy for details regarding approaches to supporting integrity. Section 2.3 and Appendix B of the policy describe various sanctions that can be applied, if there is suspected academic misconduct (e.g., contract cheating, cheating, falsification, impersonation or plagiarism).

Please visit the Academic Integrity website to understand and learn more about how to prepare and submit work so that it supports academic integrity, and to avoid academic misconduct.

All students and employees have the right to study and work in an environment that is free from discrimination and/or harassment. Language or activities that defeat this objective violate the College Policy on Discrimination/Harassment and shall not be tolerated. Information and assistance are available from the Student Conduct Office at

Accommodation for Students with Disabilities
The College will provide reasonable accommodation to students with disabilities in order to promote academic success. If you require accommodation, contact the Counselling and Accessibility Services Office at ext. 22900 to initiate the process for documenting, assessing and implementing your individual accommodation needs.