BPH633 - Biopharmaceuticals

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Last revision date Jan 4, 2021 5:44:15 PM
Last review date Jan 4, 2021 5:44:15 PM

Subject Title

Subject Description
Biopharmaceuticals represents an odyssey of history and discovery of natural and chemically modified products that are commonly employed for pharmacological interventions for a spectrum of diseases and maladies that afflict the human condition and our natural world. The subject covers both biotechnology and natural products and their applications in the area of biopharmaceutical discovery and lead compound development. Topics will include the basic principles of biotechnology, including the history of modern pharmaceuticals, encompassing ethnopharmacology and ethnomedicine procedures. Strategies for creating and improving biopharmaceuticals by combinatorial chemistry and rational drug design will be presented.  Modern techniques for recombinant protein expression, purification and large-scale biopharmaceutical process development, which encompass the future of biopharmaceuticals, including transgenic organisms and molecular biological approaches to novel biopharmaceutical drug design will be emphasized. Biopharmaceuticals are increasingly becoming central to human disease treatment and prevention, and are commonly used in the agricultural and animal husbandry fields. Collectively, students in this course will be able to utilize and build upon knowledge and principles obtained in prior courses.

Credit Status

Learning Outcomes
Upon successful completion of this subject the student will be able to:

Upon successful completion of this subject the student will be able to:

  1. Explain the basic techniques of biotechnology as they pertain to biopharmaceuticals.
  2. Interpret how biotechnology is applied to the production of modern biopharmaceuticals.
  3. Discuss how biopharmaceuticals are produced commercially and illustrate the preferred principles of the biopharmaceutical production process.
  4. Appreciate how biopharmaceuticals progressively evolve and become refined to minimize off- target effects.
  5. Integrate the methodologies associated with high throughput screening and selective side chain modification to improve and modify natural products.
  6. Combine biopharmaceutical principles to identify potential novel sources of drug lead targets and their isolation, purification and modification.
  7. Apply knowledge to improve lead targets for successful biopharmaceutical commercialization.

Essential Employability Skills

    •  Communicate clearly, concisely and correctly in the written, spoken and visual form that fulfils the purpose and meets the needs of the audience.

    •  Respond to written, spoken, or visual messages in a manner that ensures effective communication.

    •  Apply a systematic approach to solve problems.

    •  Use a variety of thinking skills to anticipate and solve problems.

    •  Locate, select, organize, and document information using appropriate technology and information systems.

    •  Interact with others in groups or teams in ways that contribute to effective working relationships and the achievement of goals.

    •  Manage the use of time and other resources to complete projects.

    •  Take responsibility for one's own actions, decisions, and consequences.

Academic Integrity
Seneca upholds a learning community that values academic integrity, honesty, fairness, trust, respect, responsibility and courage. These values enhance Seneca's commitment to deliver high-quality education and teaching excellence, while supporting a positive learning environment. Ensure that you are aware of Seneca's Academic Integrity Policy which can be found at: http://www.senecacollege.ca/about/policies/academic-integrity-policy.html Review section 2 of the policy for details regarding approaches to supporting integrity. Section 2.3 and Appendix B of the policy describe various sanctions that can be applied, if there is suspected academic misconduct (e.g., contract cheating, cheating, falsification, impersonation or plagiarism).

Please visit the Academic Integrity website http://open2.senecac.on.ca/sites/academic-integrity/for-students to understand and learn more about how to prepare and submit work so that it supports academic integrity, and to avoid academic misconduct.

All students and employees have the right to study and work in an environment that is free from discrimination and/or harassment. Language or activities that defeat this objective violate the College Policy on Discrimination/Harassment and shall not be tolerated. Information and assistance are available from the Student Conduct Office at student.conduct@senecacollege.ca.

Accommodation for Students with Disabilities
The College will provide reasonable accommodation to students with disabilities in order to promote academic success. If you require accommodation, contact the Counselling and Accessibility Services Office at ext. 22900 to initiate the process for documenting, assessing and implementing your individual accommodation needs.